phase 0 | initial rapid depolarization and the overshoot | due to opening of voltage-gated Na+ channels |
phase 1 | initial rapid repolarization | due to closure of Na+ channels & also opening of K+ channels |
phase 2 | plateau | due to a slower but prolonged opening of voltage-gated Ca2+ channels. |
phase 3 to phase 4 | Final repolarization to the resting membrane potential | due to closure of the Ca2+ channels and K+ efflux through various types of K+ channels. |
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